Progress on the Asymmetric Diels-Alder Reaction ofα,β-Unsaturated Carbonyl Compounds

Diels-Alder reaction is a [4＋2] concerted cycloaddition reaction, which has attracted considerable attention since its discovery.Asymmetric Diels-Alder reaction is an effective method for synthesis of chiral intermediates, so it was widely applied in the total synthesis of drugs and natural products.α,β-Unsaturated carbonyl compounds are a kind of highly reactive versatile intermediates in organic synthesis, according to its structural characteristics and catalytic types, recent advances in asymmetric normal electron-demand Diels-Alder reaction of α,β-unsaturated carbonyl compounds are reviewed in this paper.