Analysis of exposure to pesticide residues from Traditional Chinese Medicine

农药残留 杀虫剂 探索者 毒理 危险系数 多菌灵 化学 环境化学 重金属 生物 杀菌剂 植物 农学
作者
Jinjing Xiao,Xing Xu,Fan Wang,Jinjuan Ma,Min Liao,Yanhong Shi,Qingkui Fang,Haiqun Cao
出处
期刊:Journal of Hazardous Materials [Elsevier BV]
卷期号:365: 857-867 被引量:130
标识
DOI:10.1016/j.jhazmat.2018.11.075
摘要

The safety of Traditional Chinese Medicine (TCM) is of concern worldwide. Herein, Paeoniae Radix Alba, Chaenomelis Fructus and Moutan Cortex, representing three medicinal components, were subjected to toxicological analysis to investigate possible pesticide contamination. Exposure using a point estimate model identified 47 residues that were simultaneously validated by the QuEChERS-UPLC-MS/MS method, which is sufficiently reliable for measuring residue concentrations. Of the 313 samples tested, 94.57% contained pesticide residues, with concentrations ranging from 0.10 to 1199.84 μg kg-1, of which >83.17% contained 4-15 different residues. Carbendazim was the most frequently detected pesticide (>85%), and procymidone, pendimethalin and phoxim were also abundant (median concentration = 15.33-623.12 μg kg-1). Risk assessment based on the hazard quotient/hazard index (HQ/HI) approach revealed that exposure to pesticide residues in all three TCMs (95th percentile) were far below levels that might pose a health risk. However, insecticides contributed to cumulative exposure, especially phoxim, and worryingly, several banned pesticides were detected. The results are of theoretical and practical value for evaluating the safety TCMs, and could improve their quality and safety.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刚刚
1秒前
2秒前
3秒前
醒醒完成签到,获得积分10
5秒前
5秒前
123发布了新的文献求助10
5秒前
史迪仔完成签到,获得积分10
6秒前
Fengh发布了新的文献求助10
6秒前
今后应助复杂的问玉采纳,获得10
7秒前
8秒前
lzz发布了新的文献求助10
8秒前
dhjic发布了新的文献求助10
9秒前
9秒前
9秒前
Alvess完成签到 ,获得积分10
11秒前
共享精神应助123采纳,获得10
12秒前
大象发布了新的文献求助10
13秒前
13秒前
14秒前
15秒前
15秒前
西红柿发布了新的文献求助10
17秒前
大象完成签到,获得积分10
18秒前
18秒前
开朗艳一发布了新的文献求助10
18秒前
赘婿应助彭彭采纳,获得10
19秒前
深情安青应助科研通管家采纳,获得10
19秒前
沐言发布了新的文献求助10
19秒前
FashionBoy应助科研通管家采纳,获得10
19秒前
ding应助科研通管家采纳,获得10
19秒前
SciGPT应助科研通管家采纳,获得10
19秒前
19秒前
19秒前
隐形曼青应助科研通管家采纳,获得10
19秒前
丘比特应助科研通管家采纳,获得10
19秒前
丘比特应助怪咖采纳,获得10
19秒前
20秒前
lzz完成签到,获得积分10
20秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975658
求助须知:如何正确求助?哪些是违规求助? 3519986
关于积分的说明 11200481
捐赠科研通 3256410
什么是DOI,文献DOI怎么找? 1798247
邀请新用户注册赠送积分活动 877490
科研通“疑难数据库(出版商)”最低求助积分说明 806376