Copper‐Catalyzed Defluorinative Thioannulation of Trifluoropropynes for the Synthesis of 1,2‐Dithiole‐3‐thiones

Abstract A simple and practical strategy for the preparation of 1,2‐dithiole‐3‐thiones via copper‐catalyzed defluorinative thioannulation of trifluoropropynes has been developed using elemental sulfur as the sole sulfur source. This reaction displays a wide substrate scope and high functional group tolerance to afford the corresponding S‐heterocycles in moderate to good yields and features efficient construction of multiple C−S bonds through C−F bond cleavage of CF 3 groups. magnified image