统计学家
区间(图论)
统计
样本量测定
置信区间
计算机科学
样品(材料)
简单(哲学)
设计矩阵
基质(化学分析)
可靠性工程
数学
工程类
线性模型
化学
认识论
组合数学
哲学
色谱法
出处
期刊:RePEc: Research Papers in Economics - RePEc
日期:2020-07-15
摘要
The modified Toxicity Probability Interval design is an attempt to implement a method that is as simple as a 3+3 decision but based on statistical distributions rather than a pure rule-based approach. This method produces decision making tables for the fully trial so a statistician need not be involved in all the dose escalation decisions. The command mtpi performs simulations to find the operating characteristics alongside the decision matrix given a sample size and number of DLTs.
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