Widespread Metastatic Gastric Signet-Ring Cell Carcinoma Shown by 68Ga-FAPI PET/CT

Abstract The present study compared 68 Ga-FAPI and 18 F-FDG PET/CT in a patient with GSRCC (gastric signet-ring cell carcinoma). In this case, 68 Ga-FAPI PET/CT shows much higher tumor-to-background contrast of primary tumor and reveals more metastatic lesions than 18 F-FDG PET/CT. This case demonstrates that 68 Ga-FAPI PET/CT outperforms 18 F-FDG in identifying both primary and metastatic lesions in GSRCC.