化学
硫代酰胺
催化作用
钴
分子间力
硫黄
功能群
组合化学
分子
药物化学
立体化学
有机化学
聚合物
作者
Pengpeng Gao,Xiaohui Zhang,Qing‐Zhong Zheng
摘要
An efficient inexpensive cobalt(III)-catalyzed intermolecular amidation of N,N-dialkyl thiobenzamides with 1,4,2-dioxazol-5-ones via C-H bond activation is described. The reaction proceeds with high functional group tolerance under external oxidant free conditions, providing a straightforward approach for the direct modification of thioamide derivatives, which are prevalent organic motifs found in vital biological and pharmaceutical molecules.
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