机械生物学
机械转化
细胞力学
生物相容性材料
材料科学
纳米技术
细胞生物学
生物物理学
细胞
化学
神经科学
工程类
生物医学工程
生物
细胞骨架
生物化学
出处
期刊:Elsevier eBooks
[Elsevier]
日期:2021-01-01
卷期号:: 23-42
被引量:1
标识
DOI:10.1016/b978-0-12-823990-2.00002-7
摘要
Cells are sensitive to their surrounding microenvironment. The microscopic length scale of single cells makes it challenging to study how cells sense, interpret, and transform complex microenvironmental cues into cellular responses. The micropost and micropillar array fabricated using biocompatible elastomers has been shown as a useful tool to investigate cell-generated dynamic forces in response to microenvironmental cues. Such studies provide important insights into the underlying mechanism of cellular mechanotransduction. In this chapter, we will provide an overview of the fabrication and functionalization of micropillar and micropost arrays and highlight the utility of these systems for cell mechanics and mechanobiological studies.
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