聚酮
加氧酶
生物合成
酶
立体化学
化学
代谢工程
生物化学
计算生物学
生物
作者
Takayoshi Awakawa,Takahiro Mori,Richiro Ushimaru,Ikuro Abe
摘要
The α-ketoglutarate dependent oxygenases catalyze remarkable chemistries in polyketide-derived fungal meroterpenoid biosynthesis. This review summarizes recent progress in the structure-based engineering of these enzymes.
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