分子内力
化学
炔烃
二乙基锌
立体化学
组合化学
催化作用
有机化学
对映选择合成
作者
Seydou Kassamba,Alejandro Pérez‐Luna,Franck Ferreira,Muriel Durandetti
摘要
Intramolecular alkyne germylzincation giving access to a wide range of germoles is achieved from triarylhydrogermanes in the presence of diethylzinc and AIBN as radical initiator. The reaction proceeds through activation of the Ge-H bond, leading to a heteroarylzinc intermediate after cyclisation, which can then be involved in a post-functionalisation reaction. Our results show that only 5-endo-dig cyclizations occur, with benzogermoles being exclusively obtained.
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