免疫学
过敏性哮喘
肿瘤坏死因子α
医学
哮喘
炎症
作者
Antonie Lechner,Fiona Henkel,Franziska Hartung,Sina Bohnacker,Francesca Alessandrini,Ekaterina O. Gubernatorova,Marina S. Drutskaya,Carlo Angioni,Yannick Schreiber,Pascal Haimerl,Yan Ge,Dominique Thomas,Agnieszka M. Kabat,Edward J. Pearce,Caspar Ohnmacht,Sergei A. Nedospasov,Peter J. Murray,Adam Chaker,Carsten B. Schmidt‐Weber,Julia Esser‐von Bieren
标识
DOI:10.1016/j.jaci.2021.11.026
摘要
Allergen-triggered inflammation drives a TNF-dependent innate memory, which may perpetuate and exacerbate chronic type 2 airway inflammation and thus represents a target for asthma therapy.
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