Craving among individuals with stimulant use disorder in residential social model-based treatment – Can exercise help?

渴求 随机对照试验 可视模拟标度 医学 兴奋剂 物理疗法 心理学 临床心理学 精神科 上瘾 内科学
作者
Bilal A. Salem,Rachel Gonzales-Castaneda,Alfonso Ang,Richard A. Rawson,Daniel Dickerson,Joy Chudzynski,Jose Peñate,Brett A. Dolezal,Christopher B. Cooper,Larissa Mooney
出处
期刊:Drug and Alcohol Dependence [Elsevier BV]
卷期号:231: 109247-109247 被引量:7
标识
DOI:10.1016/j.drugalcdep.2021.109247
摘要

In a randomized controlled 8-week trial, we examined the efficacy of aerobic and resistance exercise in reducing craving for methamphetamine (MA) among individuals with MA-use disorder during residential treatment.Individuals with MA use disorder (138) who were newly enrolled in residential treatment volunteered for random assignment to either an 8-week exercise intervention (EX) or health education control (HE), with both conditions meeting 3 times weekly; 3 dropped out of the trial, bringing the analysis sample to 135. The majority of participants were male (80%), and 48% were Latino/Hispanic. The mean age of the sample was 31.7 (SD = 6.9) years. Using multivariate mixed models, differences between conditions were examined in: (1) craving for MA, measured by self-reported ratings on a Visual Analog Scale over the 8-week trial and, (2) MA use, measured by self-report and urine drug screens at baseline and 30 and 60 days after discharge from the 8-week study.Results revealed significantly lower craving scores among the participants in the EX group than those in the HE group over the 8-week trial (median daily craving score for EX = 13.5, for HE = 21.8; p = .009). In addition, participants with less craving during treatment had significantly lower rates of MA use after discharge than participants with high craving measured at 30-days (p = .004) and 60-days post-discharge (p < .001).Results support the utility of incorporating a structured exercise program for individuals with MA-use disorder to reduce craving and improve MA-use outcomes.
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