Improvement of target coverage using automated non-coplanar volumetric modulated arc therapy planning in stereotactic radiotherapy for cervical metastatic spinal tumors

医学 核医学 放射治疗 剂量学 放射治疗计划 放射外科 放射科 外科
作者
Shingo Ohira,Toshiki Ikawa,Shoki Inui,Naoyuki Kanayama,Yoshihiro Ueda,Michihiko Miyazaki,Teiji Nishio,Masahiko Koizumi,Koji Konishi
出处
期刊:Medical Dosimetry [Elsevier]
卷期号:48 (3): 197-201 被引量:2
标识
DOI:10.1016/j.meddos.2023.04.001
摘要

This study aimed to compare dosimetric parameters for targets and organs at risk (OARs) between volumetric modulated arc therapy (VMAT) and automated VMAT (HyperArc, HA) plans in stereotactic radiotherapy for patients with cervical metastatic spine tumors. VMAT plans were generated for 11 metastases using the simultaneous integrated boost technique to deliver 35 to 40 and 20 to 25 Gy for high dose and elective dose planning target volume (PTVHD and PTVED), respectively. The HA plans were retrospectively generated using 1 coplanar and 2 noncoplanar arcs. Subsequently, the doses to the targets and OARs were compared. The HA plans provided significantly higher (p < 0.05) Dmin (77.4 ± 13.1%), D99% (89.3 ± 8.9%), and D98% (92.5 ± 7.7%) for gross tumor volume (GTV) than those of the VMAT plans (73.4 ± 12.2%, 84.2 ± 9.6 and 87.3 ± 8.8% for Dmin, D99% and D98%, respectively). In addition, D99% and D98% for PTVHD were significantly higher in the HA plans, whereas dosimetric parameters were comparable between the HA and VMAT plans for PTVED. The Dmax values for the brachial plexus, esophagus, and spinal cord were comparable, and no significant difference was observed in the Dmean for the larynx, pharyngeal constrictor, thyroid, parotid grand (left and right), and Submandibular gland (left and right). The HA plans provided significantly higher target coverage of GTV and PTVHD, with a comparable dose for OARs with VMAT plans. The results of this study may contribute to the improvement of local control in clinical practice.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
科研通AI2S应助VPN不好用采纳,获得10
1秒前
冉冉完成签到,获得积分10
4秒前
4秒前
7秒前
尹俊采完成签到,获得积分10
8秒前
在水一方应助冉冉采纳,获得10
10秒前
在水一方应助LSM采纳,获得10
10秒前
充电宝应助0033采纳,获得10
13秒前
14秒前
15秒前
稻草人完成签到 ,获得积分10
16秒前
牛马刘完成签到,获得积分10
17秒前
18秒前
啦啦啦啦啦完成签到,获得积分10
18秒前
ylf发布了新的文献求助10
19秒前
haha完成签到,获得积分10
19秒前
皇甫飞扬发布了新的文献求助10
20秒前
21秒前
所所应助榆木小鸟采纳,获得10
21秒前
禹代秋完成签到,获得积分10
22秒前
机智又蓝完成签到 ,获得积分10
22秒前
小斯完成签到,获得积分10
22秒前
西陆完成签到,获得积分10
22秒前
rorraine_xu发布了新的文献求助10
23秒前
LSM发布了新的文献求助10
24秒前
迷城发布了新的文献求助10
24秒前
潘润朗完成签到 ,获得积分10
24秒前
小董不懂发布了新的文献求助10
24秒前
29秒前
32秒前
邵洋完成签到,获得积分10
32秒前
愉快的海发布了新的文献求助10
34秒前
迷城完成签到,获得积分10
35秒前
Owen应助rorraine_xu采纳,获得10
36秒前
ccl发布了新的文献求助10
37秒前
叶颤完成签到,获得积分10
38秒前
38秒前
陈陈欲睡完成签到,获得积分10
39秒前
善学以致用应助平常成仁采纳,获得10
39秒前
dangan发布了新的文献求助10
45秒前
高分求助中
Evolution 3rd edition 1500
Lire en communiste 1000
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 700
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 700
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
2-Acetyl-1-pyrroline: an important aroma component of cooked rice 500
Ribozymes and aptamers in the RNA world, and in synthetic biology 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3180905
求助须知:如何正确求助?哪些是违规求助? 2831086
关于积分的说明 7983117
捐赠科研通 2493070
什么是DOI,文献DOI怎么找? 1329957
科研通“疑难数据库(出版商)”最低求助积分说明 635872
版权声明 602954