Improvement of target coverage using automated non-coplanar volumetric modulated arc therapy planning in stereotactic radiotherapy for cervical metastatic spinal tumors

医学 核医学 放射治疗 剂量学 放射治疗计划 放射外科 放射科 外科
作者
Shingo Ohira,Toshiki Ikawa,Shoki Inui,Naoyuki Kanayama,Yoshihiro Ueda,Michihiko Miyazaki,Teiji Nishio,Masahiko Koizumi,Koji Konishi
出处
期刊:Medical Dosimetry [Elsevier]
卷期号:48 (3): 197-201 被引量:2
标识
DOI:10.1016/j.meddos.2023.04.001
摘要

This study aimed to compare dosimetric parameters for targets and organs at risk (OARs) between volumetric modulated arc therapy (VMAT) and automated VMAT (HyperArc, HA) plans in stereotactic radiotherapy for patients with cervical metastatic spine tumors. VMAT plans were generated for 11 metastases using the simultaneous integrated boost technique to deliver 35 to 40 and 20 to 25 Gy for high dose and elective dose planning target volume (PTVHD and PTVED), respectively. The HA plans were retrospectively generated using 1 coplanar and 2 noncoplanar arcs. Subsequently, the doses to the targets and OARs were compared. The HA plans provided significantly higher (p < 0.05) Dmin (77.4 ± 13.1%), D99% (89.3 ± 8.9%), and D98% (92.5 ± 7.7%) for gross tumor volume (GTV) than those of the VMAT plans (73.4 ± 12.2%, 84.2 ± 9.6 and 87.3 ± 8.8% for Dmin, D99% and D98%, respectively). In addition, D99% and D98% for PTVHD were significantly higher in the HA plans, whereas dosimetric parameters were comparable between the HA and VMAT plans for PTVED. The Dmax values for the brachial plexus, esophagus, and spinal cord were comparable, and no significant difference was observed in the Dmean for the larynx, pharyngeal constrictor, thyroid, parotid grand (left and right), and Submandibular gland (left and right). The HA plans provided significantly higher target coverage of GTV and PTVHD, with a comparable dose for OARs with VMAT plans. The results of this study may contribute to the improvement of local control in clinical practice.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
zyy完成签到,获得积分20
1秒前
2秒前
baomingqiu完成签到,获得积分10
2秒前
顾矜应助sdasdd10采纳,获得10
2秒前
2秒前
共享精神应助吉吉国王采纳,获得10
2秒前
2秒前
戴岱完成签到,获得积分10
2秒前
小二郎应助研友_59AB85采纳,获得10
2秒前
2秒前
2秒前
星辰大海应助Dprisk采纳,获得10
2秒前
3秒前
春夏秋冬应助忧伤的井采纳,获得10
3秒前
自由白卉完成签到,获得积分20
3秒前
3秒前
俊逸的咖啡完成签到,获得积分10
4秒前
FEleta完成签到,获得积分10
4秒前
混子发布了新的文献求助10
4秒前
初心发布了新的文献求助10
4秒前
4秒前
任我行发布了新的文献求助10
5秒前
绿光之城发布了新的文献求助10
6秒前
红柚完成签到,获得积分10
6秒前
7秒前
Hello应助小毕可乐采纳,获得30
7秒前
7秒前
害羞中蓝发布了新的文献求助10
7秒前
zhangdong完成签到,获得积分10
7秒前
aaronpancn发布了新的文献求助10
8秒前
自由白卉发布了新的文献求助10
8秒前
窝趣嘞完成签到 ,获得积分10
8秒前
onmymark完成签到,获得积分10
9秒前
advance完成签到,获得积分10
9秒前
tsy完成签到 ,获得积分10
10秒前
Cheetahhh完成签到,获得积分10
10秒前
孙成成完成签到 ,获得积分10
11秒前
12秒前
上官若男应助绿光之城采纳,获得10
12秒前
高分求助中
Write Like a Chemist: A Guide and Resource (第二版) 600
Mixed-anion Compounds 600
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
Earth System Geophysics 500
Aspects of Babylonian celestial divination: the lunar eclipse tablets of Enūma Anu Enlil 500
Geochemistry, 2nd Edition 地球化学经典教科书第二版 401
2024 Medicinal Chemistry Reviews 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3201273
求助须知:如何正确求助?哪些是违规求助? 2850854
关于积分的说明 8074942
捐赠科研通 2514733
什么是DOI,文献DOI怎么找? 1347411
科研通“疑难数据库(出版商)”最低求助积分说明 640427
邀请新用户注册赠送积分活动 610621