亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Improvement of target coverage using automated non-coplanar volumetric modulated arc therapy planning in stereotactic radiotherapy for cervical metastatic spinal tumors

医学 核医学 放射治疗 剂量学 放射治疗计划 放射外科 放射科 外科
作者
Shingo Ohira,Toshiki Ikawa,Shoki Inui,Naoyuki Kanayama,Yoshihiro Ueda,Michihiko Miyazaki,Teiji Nishio,Masahiko Koizumi,Koji Konishi
出处
期刊:Medical Dosimetry [Elsevier]
卷期号:48 (3): 197-201 被引量:2
标识
DOI:10.1016/j.meddos.2023.04.001
摘要

This study aimed to compare dosimetric parameters for targets and organs at risk (OARs) between volumetric modulated arc therapy (VMAT) and automated VMAT (HyperArc, HA) plans in stereotactic radiotherapy for patients with cervical metastatic spine tumors. VMAT plans were generated for 11 metastases using the simultaneous integrated boost technique to deliver 35 to 40 and 20 to 25 Gy for high dose and elective dose planning target volume (PTVHD and PTVED), respectively. The HA plans were retrospectively generated using 1 coplanar and 2 noncoplanar arcs. Subsequently, the doses to the targets and OARs were compared. The HA plans provided significantly higher (p < 0.05) Dmin (77.4 ± 13.1%), D99% (89.3 ± 8.9%), and D98% (92.5 ± 7.7%) for gross tumor volume (GTV) than those of the VMAT plans (73.4 ± 12.2%, 84.2 ± 9.6 and 87.3 ± 8.8% for Dmin, D99% and D98%, respectively). In addition, D99% and D98% for PTVHD were significantly higher in the HA plans, whereas dosimetric parameters were comparable between the HA and VMAT plans for PTVED. The Dmax values for the brachial plexus, esophagus, and spinal cord were comparable, and no significant difference was observed in the Dmean for the larynx, pharyngeal constrictor, thyroid, parotid grand (left and right), and Submandibular gland (left and right). The HA plans provided significantly higher target coverage of GTV and PTVHD, with a comparable dose for OARs with VMAT plans. The results of this study may contribute to the improvement of local control in clinical practice.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
7秒前
15秒前
Gab_bb应助科研通管家采纳,获得10
15秒前
32秒前
42秒前
ph完成签到 ,获得积分10
46秒前
54秒前
爱静静举报momo求助涉嫌违规
1分钟前
一墨完成签到,获得积分10
2分钟前
2分钟前
林思完成签到,获得积分10
2分钟前
3分钟前
lz发布了新的文献求助10
3分钟前
yoona发布了新的文献求助10
3分钟前
3分钟前
bkagyin应助lz采纳,获得10
3分钟前
yoona发布了新的文献求助80
3分钟前
3分钟前
4分钟前
没时间解释了完成签到 ,获得积分10
4分钟前
Gab_bb应助科研通管家采纳,获得10
4分钟前
yoona发布了新的文献求助10
4分钟前
4分钟前
早晚完成签到 ,获得积分10
4分钟前
4分钟前
5分钟前
爱静静举报程单梦求助涉嫌违规
5分钟前
佳佳完成签到,获得积分10
5分钟前
yoona发布了新的文献求助10
5分钟前
通科研完成签到 ,获得积分10
5分钟前
5分钟前
asadmet发布了新的文献求助10
5分钟前
wanci应助张子扬采纳,获得10
5分钟前
5分钟前
5分钟前
张子扬发布了新的文献求助10
5分钟前
Aligul完成签到,获得积分10
5分钟前
6分钟前
6分钟前
yoona发布了新的文献求助10
6分钟前
高分求助中
Spray / Wall-interaction Modelling by Dimensionless Data Analysis 2000
Write Like a Chemist: A Guide and Resource (第二版) 600
Mixed-anion Compounds 600
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
Earth System Geophysics 500
Aspects of Babylonian celestial divination: the lunar eclipse tablets of Enūma Anu Enlil 500
Geochemistry, 2nd Edition 地球化学经典教科书第二版 401
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3200772
求助须知:如何正确求助?哪些是违规求助? 2850511
关于积分的说明 8072235
捐赠科研通 2514255
什么是DOI,文献DOI怎么找? 1346987
科研通“疑难数据库(出版商)”最低求助积分说明 640305
邀请新用户注册赠送积分活动 610488