Improvement of target coverage using automated non-coplanar volumetric modulated arc therapy planning in stereotactic radiotherapy for cervical metastatic spinal tumors

医学 核医学 放射治疗 剂量学 放射治疗计划 放射外科 放射科 外科
作者
Shingo Ohira,Toshiki Ikawa,Shoki Inui,Naoyuki Kanayama,Yoshihiro Ueda,Michihiko Miyazaki,Teiji Nishio,Masahiko Koizumi,Koji Konishi
出处
期刊:Medical Dosimetry [Elsevier]
卷期号:48 (3): 197-201 被引量:2
标识
DOI:10.1016/j.meddos.2023.04.001
摘要

This study aimed to compare dosimetric parameters for targets and organs at risk (OARs) between volumetric modulated arc therapy (VMAT) and automated VMAT (HyperArc, HA) plans in stereotactic radiotherapy for patients with cervical metastatic spine tumors. VMAT plans were generated for 11 metastases using the simultaneous integrated boost technique to deliver 35 to 40 and 20 to 25 Gy for high dose and elective dose planning target volume (PTVHD and PTVED), respectively. The HA plans were retrospectively generated using 1 coplanar and 2 noncoplanar arcs. Subsequently, the doses to the targets and OARs were compared. The HA plans provided significantly higher (p < 0.05) Dmin (77.4 ± 13.1%), D99% (89.3 ± 8.9%), and D98% (92.5 ± 7.7%) for gross tumor volume (GTV) than those of the VMAT plans (73.4 ± 12.2%, 84.2 ± 9.6 and 87.3 ± 8.8% for Dmin, D99% and D98%, respectively). In addition, D99% and D98% for PTVHD were significantly higher in the HA plans, whereas dosimetric parameters were comparable between the HA and VMAT plans for PTVED. The Dmax values for the brachial plexus, esophagus, and spinal cord were comparable, and no significant difference was observed in the Dmean for the larynx, pharyngeal constrictor, thyroid, parotid grand (left and right), and Submandibular gland (left and right). The HA plans provided significantly higher target coverage of GTV and PTVHD, with a comparable dose for OARs with VMAT plans. The results of this study may contribute to the improvement of local control in clinical practice.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
wilson发布了新的文献求助10
1秒前
勤奋耳机完成签到 ,获得积分10
2秒前
sure完成签到 ,获得积分10
3秒前
哈哈发布了新的文献求助10
4秒前
明理青丝完成签到 ,获得积分10
9秒前
陈炳蓉完成签到,获得积分10
12秒前
陈皮完成签到 ,获得积分10
15秒前
雪儿完成签到 ,获得积分10
17秒前
123完成签到 ,获得积分10
17秒前
keepory86完成签到,获得积分10
24秒前
大雁完成签到 ,获得积分10
25秒前
Fiona完成签到 ,获得积分10
25秒前
璐璐完成签到 ,获得积分10
26秒前
大舟Austin完成签到 ,获得积分10
31秒前
唯梦完成签到 ,获得积分10
31秒前
33秒前
韭菜发布了新的文献求助10
38秒前
Ruuo616完成签到 ,获得积分10
46秒前
wind完成签到,获得积分10
51秒前
55秒前
隐形白开水完成签到,获得积分10
57秒前
whatever应助科研通管家采纳,获得30
57秒前
LJWU应助科研通管家采纳,获得10
57秒前
whatever应助科研通管家采纳,获得30
57秒前
xx完成签到 ,获得积分10
1分钟前
131完成签到,获得积分10
1分钟前
XinEr完成签到 ,获得积分10
1分钟前
wendydqw完成签到 ,获得积分10
1分钟前
大头完成签到 ,获得积分10
1分钟前
PG完成签到 ,获得积分0
1分钟前
Akim应助韭菜采纳,获得10
1分钟前
Jessica英语好完成签到 ,获得积分10
1分钟前
c_123完成签到 ,获得积分10
1分钟前
缓慢雅青完成签到 ,获得积分10
1分钟前
贝贝完成签到 ,获得积分10
1分钟前
韭菜完成签到,获得积分20
1分钟前
CCC完成签到 ,获得积分10
1分钟前
小二郎应助高工采纳,获得10
1分钟前
寻道图强应助benben采纳,获得30
1分钟前
Ding完成签到,获得积分10
1分钟前
高分求助中
Spray / Wall-interaction Modelling by Dimensionless Data Analysis 2000
Mathematics and Finite Element Discretizations of Incompressible Navier—Stokes Flows 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
2-Acetyl-1-pyrroline: an important aroma component of cooked rice 500
A real-time energy management strategy based on fuzzy control and ECMS for PHEVs 400
Handbook on People's China (1957) 400
2024 Medicinal Chemistry Reviews 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3190111
求助须知:如何正确求助?哪些是违规求助? 2839411
关于积分的说明 8023560
捐赠科研通 2502244
什么是DOI,文献DOI怎么找? 1336398
科研通“疑难数据库(出版商)”最低求助积分说明 637841
邀请新用户注册赠送积分活动 605974