Improvement of target coverage using automated non-coplanar volumetric modulated arc therapy planning in stereotactic radiotherapy for cervical metastatic spinal tumors

医学 核医学 放射治疗 剂量学 放射治疗计划 放射外科 放射科 外科
作者
Shingo Ohira,Toshiki Ikawa,Shoki Inui,Naoyuki Kanayama,Yoshihiro Ueda,Michihiko Miyazaki,Teiji Nishio,Masahiko Koizumi,Koji Konishi
出处
期刊:Medical Dosimetry [Elsevier]
卷期号:48 (3): 197-201 被引量:2
标识
DOI:10.1016/j.meddos.2023.04.001
摘要

This study aimed to compare dosimetric parameters for targets and organs at risk (OARs) between volumetric modulated arc therapy (VMAT) and automated VMAT (HyperArc, HA) plans in stereotactic radiotherapy for patients with cervical metastatic spine tumors. VMAT plans were generated for 11 metastases using the simultaneous integrated boost technique to deliver 35 to 40 and 20 to 25 Gy for high dose and elective dose planning target volume (PTVHD and PTVED), respectively. The HA plans were retrospectively generated using 1 coplanar and 2 noncoplanar arcs. Subsequently, the doses to the targets and OARs were compared. The HA plans provided significantly higher (p < 0.05) Dmin (77.4 ± 13.1%), D99% (89.3 ± 8.9%), and D98% (92.5 ± 7.7%) for gross tumor volume (GTV) than those of the VMAT plans (73.4 ± 12.2%, 84.2 ± 9.6 and 87.3 ± 8.8% for Dmin, D99% and D98%, respectively). In addition, D99% and D98% for PTVHD were significantly higher in the HA plans, whereas dosimetric parameters were comparable between the HA and VMAT plans for PTVED. The Dmax values for the brachial plexus, esophagus, and spinal cord were comparable, and no significant difference was observed in the Dmean for the larynx, pharyngeal constrictor, thyroid, parotid grand (left and right), and Submandibular gland (left and right). The HA plans provided significantly higher target coverage of GTV and PTVHD, with a comparable dose for OARs with VMAT plans. The results of this study may contribute to the improvement of local control in clinical practice.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
NexusExplorer应助霸气鹏飞采纳,获得10
刚刚
1秒前
2秒前
勿昂完成签到 ,获得积分10
2秒前
---完成签到,获得积分20
2秒前
沐雨发布了新的文献求助10
4秒前
sabet发布了新的文献求助10
4秒前
xiaowu完成签到,获得积分10
4秒前
5秒前
娇儿完成签到,获得积分10
5秒前
葫芦壳关注了科研通微信公众号
6秒前
咿呀咿呀完成签到 ,获得积分10
7秒前
7秒前
科研通AI2S应助朴素千亦采纳,获得10
8秒前
科研通AI2S应助欣慰的绮露采纳,获得10
9秒前
xiaowu发布了新的文献求助10
9秒前
二槑发布了新的文献求助10
9秒前
10秒前
科研通AI2S应助可以的采纳,获得10
10秒前
11秒前
传统的安青完成签到 ,获得积分10
13秒前
13秒前
lvsehx发布了新的文献求助10
13秒前
LOVEMEVOL发布了新的文献求助10
14秒前
H喜欢老霉完成签到 ,获得积分20
15秒前
随机子应助直率的睫毛膏采纳,获得10
15秒前
魏白晴完成签到,获得积分10
15秒前
16秒前
16秒前
绒绒发布了新的文献求助10
16秒前
司南应助星星采纳,获得30
16秒前
16秒前
zero完成签到,获得积分20
16秒前
斯文败类应助席玲采纳,获得10
16秒前
止心所至完成签到 ,获得积分10
17秒前
17秒前
NYM完成签到 ,获得积分10
17秒前
娇娇完成签到,获得积分10
19秒前
C2发布了新的文献求助10
19秒前
高分求助中
Evolution 3rd edition 1500
保险藏宝图 1000
Lire en communiste 1000
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 700
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 700
Mathematics and Finite Element Discretizations of Incompressible Navier—Stokes Flows 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3182487
求助须知:如何正确求助?哪些是违规求助? 2832839
关于积分的说明 7990824
捐赠科研通 2494830
什么是DOI,文献DOI怎么找? 1331053
科研通“疑难数据库(出版商)”最低求助积分说明 636228
邀请新用户注册赠送积分活动 603191