化学
纳米团簇
荧光
牛血清白蛋白
激进的
荧光素
放射分析
光化学
辐照
核化学
分析化学(期刊)
放射化学
色谱法
有机化学
光学
物理
核物理学
作者
Chengfang Zhang,Yuanyuan Yang,Danni Qin,Rui Hu,Liang Hu
出处
期刊:Talanta
[Elsevier]
日期:2024-05-01
卷期号:271: 125631-125631
标识
DOI:10.1016/j.talanta.2024.125631
摘要
In this paper, we synthesized silver nanoclusters using bovine serum albumin (BSA) as a template (BSA@AgNCs). Then, we anchored hydroxyphenyl fluorescein (HPF) to yield HPF-BSA@AgNCs. When exposed to X-rays, hydroxyl (∙OH) radicals generated by radiolysis of water react with HPF to produce fluorescein, which emits enhanced fluorescence at 515 nm (λex = 480 nm). The fluorescence intensity of BSA@AgNCs at 685 nm (λex = 480 nm) remains stable when exposed to X-rays. This HPF-BSA@AgNCs ratiometric fluorescence sensor can rapidly detect 0.1-20 Gy (the energy deposited per unit mass, J/kg) of X-rays. In addition, HPF-BSA@AgNCs exhibit good durability and temperature stability. Finally, HPF-BSA@AgNCs were used to measure the absorbed doses of A549 cells and evaluate the cell irradiation damage.
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