孟德尔随机化
医学
子痫
子痫前期
联想(心理学)
产科
因果推理
随机化
怀孕
随机对照试验
内科学
遗传学
基因型
病理
基因
遗传变异
哲学
认识论
生物
作者
Juan Li,Yuling Kong,Guosu Shi,Shuxiao Dong,Sheng Wang,Liping Feng,Quanzhou Guo,LU Cai-hong
标识
DOI:10.1080/10641955.2024.2405857
摘要
Preeclampsia and eclampsia are severe pregnancy disorders marked by hypertension and potential organ damage. The etiological basis of preeclampsia and eclampsia is not fully understood. Previous studies have revealed a link between sleep abnormality and preeclampsia/eclampsia, but the causal relationship remains unclear. In this study, we explored the genetic links between sleep and preeclampsia/eclampsia using genome-wide association study (GWAS) summary data and Mendelian randomization (MR) analysis.
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