A Strategy Involving Microporous Microneedles Integrated with CAR‐TREM2‐Macrophages for Scar Management by Regulating Fibrotic Microenvironment

fibroblasts and suppressing TGFβ secretion. This, in turn, inhibits the phenotypic conversion of LRG1 ECs and provides multifactorial way of alleviating scars. This study uncovers the evidence that mMNs attached to CAR-TREM2-Ms may exert vital influences on skin scarring through the regulation of the skin scar microenvironment, providing a promising approach for treating posttraumatic scarring.