The relationship between apathy and nonparametric variables of rest activity rhythm in older adults with cerebral small vessel disease

冷漠 萧条(经济学) 心理学 观察研究 疾病 内科学 精神科 医学 宏观经济学 经济
作者
Hóngyi Zhào,Hong Li,Yulong Ding,Zhiyi Li,Yonghua Huang
出处
期刊:Chronobiology International [Taylor & Francis]
卷期号:40 (12): 1574-1581
标识
DOI:10.1080/07420528.2023.2282467
摘要

The goal of the current study was to demonstrate if the rest-activity rhythm (RAR) was altered in apathetic older adults with cerebral small vessel disease (CSVD) and find out the relationship between apathy/depression severity and RAR features in CSVD patients. This is a cross-sectional observational investigation including 53 CSVD cases (54.74% men), aged 70.70 ± 6.18 years old. The participants were assessed by neuropsychiatric inventory (NPI) subscale of apathy (NPI-apathy) and depression (NPI-depression) in succession, according to updated diagnostic criteria for apathy (DCA). Each subject wore an actigraph device (ActiGraph GT3X) in their nondominant hand for 7 days to collect raw data. Using a non-parametric methodological analysis, this study determined RAR variables such as interdaily stability (IS), intraday variability (IV) and relative amplitude (RA). Patients in the apathy-positive group had a higher Fazekas score than those in the apathy-negative group. IS, but not IV, RA, or objective sleep variables, differed between elderly patients with varying degrees of CSVD burden. Furthermore, apathy severity was statistically correlated with RA after adjusting for age, gender and education level, whereas depression severity was not associated with RAR variables. Finally, we discovered that the severity of apathy had no significant relationship with the severity of depression. All these findings indicated that the RAR altered in apathetic older adults with CSVD, and apathy was associated with decreased RAR amplitude.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
扬嘉諵发布了新的文献求助10
2秒前
精明的沅应助jiabaoyu采纳,获得10
2秒前
路路发布了新的文献求助10
2秒前
Jasper应助勤恳凡双采纳,获得10
4秒前
研友_VZG7GZ应助影子采纳,获得10
4秒前
5秒前
5秒前
梓歆发布了新的文献求助10
6秒前
科研小白完成签到,获得积分10
9秒前
李胜驳回了Ava应助
9秒前
WD发布了新的文献求助10
10秒前
量子星尘发布了新的文献求助10
10秒前
11秒前
拾寒完成签到,获得积分10
11秒前
虚幻初之发布了新的文献求助10
13秒前
小二郎应助小麻花采纳,获得10
16秒前
脑洞疼应助端庄涟妖采纳,获得10
16秒前
乖猫要努力应助sxy采纳,获得10
16秒前
99发布了新的文献求助10
17秒前
17秒前
18秒前
十一完成签到,获得积分10
18秒前
小米完成签到,获得积分20
20秒前
21秒前
21秒前
21秒前
22秒前
FashionBoy应助Sjingjia采纳,获得10
22秒前
22秒前
世界第一大庸医完成签到,获得积分10
23秒前
蓝心语发布了新的文献求助10
23秒前
24秒前
闪电侠发布了新的文献求助10
24秒前
田様应助oscarkwan采纳,获得10
24秒前
ding应助小麻花采纳,获得10
24秒前
姜玲发布了新的文献求助10
25秒前
26秒前
27秒前
素质被谁吃了完成签到,获得积分10
27秒前
28秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975516
求助须知:如何正确求助?哪些是违规求助? 3519930
关于积分的说明 11200130
捐赠科研通 3256278
什么是DOI,文献DOI怎么找? 1798183
邀请新用户注册赠送积分活动 877425
科研通“疑难数据库(出版商)”最低求助积分说明 806320