医学
肺静脉
烧蚀
心房颤动
心脏病学
内科学
接收机工作特性
核医学
作者
Wei‐Tso Chen,Fa‐Po Chung,Yenn‐Jiang Lin,Shih‐Lin Chang,Li‐Wei Lo,Yu‐Feng Hu,Ta‐Chuan Tuan,Tze‐Fan Chao,Jo‐Nan Liao,Chin‐Yu Lin,Ting‐Yung Chang,Ling Kuo,Cheng‐I Wu,Chih‐Min Liu,Shin‐Huei Liu,Yu‐Cheng Hsieh,Cheng‐Hung Li,Shih‐Ann Chen
摘要
Abstract Introduction Carina breakthrough (CB) at the right pulmonary vein (RPV) can occur after circumferential pulmonary vein isolation (PVI) due to epicardial bridging or transient tissue edema. High‐power short‐duration (HPSD) ablation may increase the incidence of RPV CB. Currently, the surrogate of ablation parameters to predict RPV CB is not well established. This study investigated predictors of RPV CB in patients undergoing ablation index (AI)‐guided PVI with HPSD. Methods The study included 62 patients with symptomatic atrial fibrillation (AF) who underwent AI‐guided PVI using HPSD. Patients were categorized into two groups based on the presence or absence of RPV CB. Lesions adjacent to the RPV carina were assessed, and CB was confirmed through residual voltage, low voltage along the ablation lesions, and activation wavefront propagation. Results Out of the 62 patients, 21 (33.87%) experienced RPV CB (Group 1), while 41 (66.13%) achieved first‐pass RPV isolation (Group 2). Despite similar AI and HPSD, patients with RPV CB had lower contact force (CF) at lesions adjacent to the RPV carina. Receiver operating characteristic (ROC) curve analysis identified CF < 10.5 g as a predictor of RPV CB, with 75.7% sensitivity and 56.2% specificity (area under the curve: 0.714). Conclusion In patients undergoing AI‐guided PVI with HPSD, lower CF adjacent to the carina was associated with a higher risk of RPV CB. These findings suggest that maintaining higher CF during ablation in this region may reduce the occurrence of RPV CB.
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