黄嘌呤
纳米棒
镧
傅里叶变换红外光谱
硫化物
化学
材料科学
水平扫描速率
扫描电子显微镜
次黄嘌呤
循环伏安法
核化学
电极
分析化学(期刊)
无机化学
电化学
纳米技术
化学工程
色谱法
生物化学
酶
冶金
复合材料
物理化学
工程类
作者
Zainab Javeed,Muhammad Ibrahim,Muhammad Faisal Iqbal,Rahat Nawaz,Dilshad Hussain,Muhammad Ayub,Muhammad Naeem Ashiq,Saadat Majeed,Muahmmad Najam-ul-Haq,Batool Fatima
出处
期刊:Journal of The Electrochemical Society
[The Electrochemical Society]
日期:2023-11-01
卷期号:170 (11): 117514-117514
被引量:1
标识
DOI:10.1149/1945-7111/ad0c69
摘要
Xanthine detection is crucial for the diagnosis of metabolic disorders like xanthinuria and gout. Xanthinuria is due to xanthine stones in the urinary tract. Earlier detection of xanthine levels in human blood can minimize the risks. In this research, a non-enzymatic xanthine sensor is fabricated by depositing different concentrations of lanthanum sulfide nanoparticles on a glassy carbon electrode (GCE). Lanthanum sulfide (La 2 S 3 ) nanorods are synthesized by a simple hydrothermal method and characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDS). The effect of pH, scan rates, and xanthine concentration on the peak current is examined. La 2 S 3 -modified GCE shows good conductivity, a large surface area, fast electron transfer, and promising sensing capability for xanthine detection. The highest anodic peak for xanthine is observed at a 1 mV s −1 scan rate. The la 2 S 3 -based sensor exhibits a limit of detection (LOD) of 1.2 μ M and xanthine recovery of up to 99.3%. The designed sensing system demonstrates the potential for xanthine detection in blood serum samples. The proposed sensor exhibits excellent efficiency due to fast electron transfer and good stability of La 2 S 3 nanorods.
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