Considering Hirschsprung‐associated enterocolitis in infants dehydration: Misdiagnosis risk and management of an underestimated lethal disease

Acta PaediatricaEarly View BRIEF REPORT Considering Hirschsprung-associated enterocolitis in infants dehydration: Misdiagnosis risk and management of an underestimated lethal disease M. Pasquinucci, Corresponding Author M. Pasquinucci [email protected] orcid.org/0009-0003-8250-6653 DINOGMI, IRCCS G. Gaslini – Children's Hospital, Genoa, Italy Correspondence M. Pasquinucci, DINOGMI, IRCCS G. Gaslini Hospital, Largo Gaslini 5, Genoa, Italy. Email: [email protected] Contribution: Conceptualization, Writing - original draft, ​InvestigationSearch for more papers by this authorG. Tardini, G. Tardini Intermediate Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Writing - original draft, Conceptualization, ​InvestigationSearch for more papers by this authorM. F. Cortella, M. F. Cortella DINOGMI, IRCCS G. Gaslini – Children's Hospital, Genoa, Italy Contribution: Writing - review & editingSearch for more papers by this authorD. Pirlo, D. Pirlo Intermediate Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Supervision, Validation, Writing - review & editingSearch for more papers by this authorA. Moscatelli, A. Moscatelli Neonatal and Pediatric Intensive Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Supervision, ValidationSearch for more papers by this author M. Pasquinucci, Corresponding Author M. Pasquinucci [email protected] orcid.org/0009-0003-8250-6653 DINOGMI, IRCCS G. Gaslini – Children's Hospital, Genoa, Italy Correspondence M. Pasquinucci, DINOGMI, IRCCS G. Gaslini Hospital, Largo Gaslini 5, Genoa, Italy. Email: [email protected] Contribution: Conceptualization, Writing - original draft, ​InvestigationSearch for more papers by this authorG. Tardini, G. Tardini Intermediate Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Writing - original draft, Conceptualization, ​InvestigationSearch for more papers by this authorM. F. Cortella, M. F. Cortella DINOGMI, IRCCS G. Gaslini – Children's Hospital, Genoa, Italy Contribution: Writing - review & editingSearch for more papers by this authorD. Pirlo, D. Pirlo Intermediate Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Supervision, Validation, Writing - review & editingSearch for more papers by this authorA. Moscatelli, A. Moscatelli Neonatal and Pediatric Intensive Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Genoa, Italy Contribution: Supervision, ValidationSearch for more papers by this author First published: 16 April 2024 https://doi.org/10.1111/apa.17246Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. CONFLICT OF INTEREST STATEMENT The Authors declare there is no conflict of interest. REFERENCES 1Gershon EM, Rodriguez L, Arbizu RA. Hirschsprung's disease associated enterocolitis: a comprehensive review. World J Clin Pediatr. 2023; 12(3): 68-76. doi:10.5409/wjcp.v12.i3.68 10.5409/wjcp.v12.i3.68 Google Scholar 2Peruzzo M, Milani GP, Garzoni L, et al. Body fluids and salt metabolism – part II. Ital J Pediatr. 2010; 36(1): 78. doi:10.1186/1824-7288-36-78 10.1186/1824-7288-36-78 Google Scholar 3Gosain A, Frykman PK, Cowles RA, et al. Guidelines for the diagnosis and management of Hirschsprung-associated enterocolitis. Pediatr Surg Int. 2017; 33(5): 517-521. doi:10.1007/s00383-017-4065-8 10.1007/s00383-017-4065-8 PubMedWeb of Science®Google Scholar 4Li S, Zhang Y, Li K, et al. Update on the pathogenesis of the Hirschsprung-associated enterocolitis. Int J Mol Sci. 2023; 24(5): 4602. doi:10.3390/ijms24054602 10.3390/ijms24054602 CASWeb of Science®Google Scholar 5Ahmad H, Rentea RM, Knaus ME, et al. Routine botulinum toxin injection one month after a Swenson pull-through does not change the incidence of Hirschsprung associated enterocolitis. J Pediatr Surg. 2022; 57(8): 1453-1457. doi:10.1016/j.jpedsurg.2021.11.029 10.1016/j.jpedsurg.2021.11.029 Web of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation