Amino-functionalized cross-linked cellulosic fabric with antibacterial, UV protection, and coloring effects using folic acid

The amino-functionalized cellulose with folic acid, via an esterification reaction between carboxylic acid of folic acid and hydroxyl groups of cellulose, can develop multifunctional products with new chemical and physical properties. Folic acid contains two carboxylic groups as well as an amine group that can be used as a coupling agent and provide suitable conditions for coupling hydroxyl-based compounds to cellulose. Also; the multi-functionalized cellulose with folic acid has no effects on the physical and mechanical properties and also has benefits such as antibacterial, UV protection, and wrinkle resistance. The FTIR-ATR and Raman analysis confirmed the amino functionalized-cellulosic fabric via an esterification reaction between cellulose and folic acid. The cell viability of L929 fibroblast (NCBI C161) and MCF-7 (NCBI C135) cancer cells indicated more effectiveness on MCF-7 cancer cells. Therefore; folic acid can be used as a biocompatible natural cross-linker to modify cellulose fabrics for apparel and medical applications. • Introducing folic acid (vitamin B9) as a novel friendly cellulose cross-linking agent • Formation of yellow-brown color on the cellulosic fabric • Producing UV-protection cellulosic fabric along with other properties • Antibacterial feature with compatible L929-cell • MCF-7 cell mortality by using folic acid (7 %) on cellulosic fabric