Cross-ancestry genome-wide association studies of brain imaging phenotypes

生物表型全基因组关联研究遗传学基因组遗传关联进化生物学计算生物学单核苷酸多态性基因型基因

作者

Jilian Fu,Quan Zhang,Jianhua Wang,Meiyun Wang,Bing Zhang,Wenzhen Zhu,Shijun Qiu,Zuojun Geng,Guangbin Cui,Yongqiang Yu,Weihua Liao,Hui Zhang,Bo Gao,Xiaojun Xu,Tong HAN,Zhenwei Yao,Wen Qin,Feng Liu,Meng Liang,Sijia Wang,Qiang Xu,Jiayuan Xu,Peng Zhang,Wei Li,Dapeng Shi,Caihong Wang,Su Lui,Zhihan Yan,Feng Chen,Jing Zhang,Jiance Li,Wen Shen,Yanwei Miao,Dawei Wang,Junfang Xian,Jia‐Hong Gao,Xiaochu Zhang,Kai Xu,Xi‐Nian Zuo,Long Jiang Zhang,Zhaoxiang Ye,Jingliang Cheng,Mulin Jun Li,Chunshui Yu,Quan Zhang,Junping Wang,Xue Zhang,Xinjun Suo,Congcong Yuan,Yuan Ji,Hui Xue,Tianying Gao,Junpeng Liu,Yanjun Li,Xi Guo,Lixue Xu,Jiajia Zhu,Huaigui Liu,Fangshi Zhao,Jie Sun,Yongjie Xu,Huanhuan Cai,Jie Tang,Yaodan Zhang,Yongqin Xiong,Xianting Sun,Nannan Pan,Xue Zhang,Jiayang Yang,Nana Liu,Ya Wen,Dan Zhu,Bingjie Wu,Wenshuang Zhu,Qingqing Diao,Yujuan Cao,Bingbing Yang,Lining Guo,Yingying Xie,Jiahui Lin,Zhimin Li,Yan Zhang,Kaizhong Xue,Z. Wang,Junlin Shen,Xuejun Zhang,Hao Ding,Qian Su,Shijie Zhang,Ma Lun,Yan Bai,Min Guan,Wei Wei,Peifang Miao,Fuhong Duan,Yafei Guo,Weijian Wang,Lijuan Zheng,Li Lin,Yunfei Wang,Han Zhang,Qian Zhang,Qing Zhao,Sichu Wu,Junxia Wang,Yi Sun,Yang He,Zhe Zhang,Yinshan Wang,Quan Zhou,Tian Tian,Yi Liang,Yujie Liu,Hui Zeng,Jingxian Chen,Haitao Ge,Peng Xu,Cailuan Lu,Wu Chen,Xiaoying Yang,Yuzhao Wang,Yankai Wu,Xuran Feng,Ling Li,Duo Gao,Rujing Zha,Ying Li,Lizhuang Yang,Ying Chen,Ling Zuo,Jianqiao Ge,Guo‐Yuan Yang,Wen Wang,Lin‐Feng Yan,Yang Yang,Jin Zhang,Qian Wang,Xiaoxia Qu,Ying Wang,Fei Yuan,Li Hu,Jizhen Li,Weiwei Wang,Yujing Zhou,Miaomiao Long,Lihua Liu,LI Xiao-hu,Xiaoshu Li,Yunjun Yang,Nengzhi Xia,Shuai Yang,Youming Zhang,Guangyao Liu,Laiyang Ma,Xiaochun Wang,Ying Lei,Gang Zhang,Kang Yuan,Jingjing Xu,Xiaojun Guan,Yuankai Lin,Huijuan Chen,Yuchuan Fu,Yi Lü,Jun Guo,Hao Lü,Yue Wu

出处

期刊：Nature Genetics [Springer Nature]
日期：2024-05-29 卷期号：56 (6): 1110-1120 被引量：2

链接

researchsquare.com nih.govdoi.org

标识

DOI：10.1038/s41588-024-01766-y

摘要

Genome-wide association studies of brain imaging phenotypes are mainly performed in European populations, but other populations are severely under-represented. Here, we conducted Chinese-alone and cross-ancestry genome-wide association studies of 3,414 brain imaging phenotypes in 7,058 Chinese Han and 33,224 white British participants. We identified 38 new associations in Chinese-alone analyses and 486 additional new associations in cross-ancestry meta-analyses at P < 1.46 × 10

求助该文献

最长约 10秒，即可获得该文献文件

Cross-ancestry genome-wide association studies of brain imaging phenotypes

今日热心研友