Ir‐Catalyzed α‐Alkylation of Methyl Ketones with Primary Carbohydrate Alcohols

Abstract Iridium‐catalyzed α‐alkylation of methyl ketones with primary carbohydrate alcohols proceeded via borrowing hydrogen strategy. Protected sugar derivatives having one free primary hydroxyl group reacted with methyl ketones to give the α‐alkylation products or alkylated 4,5‐unsaturated sugars along with the elimination of an alkoxy group. magnified image