Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study
医学
观察研究
癌症
血液检验
内科学
恶性肿瘤
前瞻性队列研究
作者
Brian D Nicholson,Jason Oke,Pradeep S. Virdee,Dean Harris,Catherine O‘Doherty,John ES Park,Zaed Hamady,Vinay Sehgal,Andrew Millar,Louise Medley,Sharon Tonner,Monika Vargová,Lazarina Engonidou,Kaveh Riahi,Ying Luan,Sara Hiom,Harpal Kumar,Harit Nandani,Kathryn N. Kurtzman,Ly‐Mee Yu,Clare Freestone,Sarah Pearson,FD Richard Hobbs,Rafael Perera,Mark R. Middleton
Analysis of circulating tumour DNA could stratify cancer risk in symptomatic patients. We aimed to evaluate the performance of a methylation-based multicancer early detection (MCED) diagnostic test in symptomatic patients referred from primary care.
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(2025-6-4)
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