屎肠球菌
粪肠球菌
生物膜
微生物学
肠球菌
抗生素
细菌
生物
利福平
金黄色葡萄球菌
遗传学
作者
Anna Holmberg,Magnus Rasmussen
标识
DOI:10.1016/j.diagmicrobio.2015.09.012
摘要
Enterococcus faecalis and Enterococcus faecium are important nosocomial pathogens that form biofilms on implanted materials. We compare the antibiotic sensitivity of bacteria in new (established during 24 hours) and mature (established during 120 hours) enterococcal biofilms. Mature biofilms contained more bacteria and were much more tolerant to antibiotics, including rifampicin-containing combinations, as judged by determination of minimal biofilm eradication concentrations and by time-kill experiments of bacteria in biofilms formed on beads of bone cement.
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