镧系元素
化学
发光
生物分子
发光测量
碱基
分析物
纳米技术
组合化学
离子
物理化学
有机化学
材料科学
光电子学
DNA
生物化学
作者
Xiaohui Wang,Hongjin Chang,Juan Xie,Baozhou Zhao,Botong Liu,Shuilin Xu,Wenbo Pei,Na Ren,Ling Huang,Wei Huang
标识
DOI:10.1016/j.ccr.2014.02.001
摘要
Lanthanide-based luminescent probes have attracted increasing attention due to their unique optical properties, such as large Stokes and/or anti-Stokes shifts, long luminescence lifetimes (up to milliseconds), and narrow and compound-independent emission bands, making them widely employed in detection, diagnosis, and bioimaging. This review focuses on the recent developments of lanthanide-based luminescent probes including lanthanide complexes and lanthanide nanoparticles for probing pH, anions, metal ions, reactive oxygen species, and biomolecules (amino acids, proteins, nucleobases, and nucleic acids). The design principles and recognition mechanisms of luminescent probes based on lanthanide ions for various analytes are elaborated in detail. In the end, future research directions with great potentials and the according challenges of lanthanide-based luminescent probes are also discussed.
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