神经科学
细胞内
神经生理学
锌
生物
化学
细胞生物学
有机化学
作者
Stefano L. Sensi,Pierre Paoletti,Ashley I. Bush,Israel Sekler
摘要
The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful tools, including zinc-sensitive fluorescent probes, selective chelators and genetically modified animal models, has brought a deeper understanding of the roles of this cation as a crucial intra- and intercellular signalling ion of the CNS, and hence of the neurophysiological importance of zinc-dependent pathways and the injurious effects of zinc dyshomeostasis. The development of some innovative therapeutic strategies is aimed at controlling and preventing the damaging effects of this cation in neurological conditions such as stroke and Alzheimer's disease.
科研通智能强力驱动
Strongly Powered by AbleSci AI