The Transdermal Absorption Study of Human-Like Collagen

This paper focuses on the properties of the transdermal absorption of Human-like collagen (HLC). In present study, fluorescent marker (isothiocyanates were fluorescent element) was used to detect the absorptivity of HLC and gelatin was considered as a control. 2% HLC solution, 2% gelatin solution, a mixture of 2% HLC and azone, a mixture of 2% gelatin and azone were prepared, respectively. And then this solution was smeared on skin of mice. After 4h and 8h, the skin were collected and observed under a fluorescence microscope. In conclusion, pure human-like collagen has certain transdermal absorption and azone promote the transdermal absorption property of Human like collagen in comparison with gelatin.