Radical cyclization of 1-allyloxy-2-halo-1-silacyclopentane. Application to stereoselective synthesis of 1,4,6-triols

Abstract Treatment of 1-allyloxy-1-phenyl-2-bromo-1-silacyclopentane with n-Bu3SnH in the presence of catalytic amount of Et3B provided 1-sila-2-oxabicyclo[3.3.0]-octane which was converted into 1,4,6-triol.