分子医学
褪黑素
癌基因
细胞周期
呼吸系统
医学
癌症
生物
生理学
计算生物学
癌症研究
化学
内科学
作者
Lijie Li,Xiaochao Gang,Jiajia Wang,Xiaoyan Gong
出处
期刊:Experimental and Therapeutic Medicine
[Spandidos Publications]
日期:2022-02-09
卷期号:23 (4)
被引量:5
标识
DOI:10.3892/etm.2022.11197
摘要
Melatonin, primarily secreted by the pineal gland, is an anthracemal compound. Its chemical name is N‑acetyl‑5‑methoxytryptamine. Great advances in melatonin‑related research have been made, including the understanding of its roles in the rhythm of the sleep/wake cycle, retardation of aging processes, as well as antioxidant and/or anti‑inflammatory effects. Melatonin exerts a wide range of physiological effects related to the high lipophilicity of melatonin itself. Melatonin has strong radical scavenging activity, which serves an important role in pulmonary disorders. Pulmonary disorders are among the diseases that threaten human health. Especially in developing countries, due to environmental factors such as smoke and dust, the incidences of pulmonary disorders are high. Melatonin has been reported to have great potential to treat patients with pulmonary disorders. The present review discusses the relationship between melatonin and pulmonary disorders, including coronavirus disease‑2019, chronic obstructive pulmonary disease, non‑small cell lung cancer and pulmonary fibrosis.
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