电源1
对氧磷酶
癌症
氧化应激
炎症
医学
生物信息学
生物
免疫学
基因
内科学
遗传学
基因型
作者
Irma Martha Medina-Díaz,N. Ponce-Ruíz,Aurora Elizabeth Rojas-García,José Francisco Zambrano-Zargoza,Yael Yvette Bernal-Hernández,Cyndia Azucena González-Arias,Briscia Socorro Barrón-Vivanco,José Francisco Herrera-Moreno
出处
期刊:Antioxidants
[MDPI AG]
日期:2022-03-31
卷期号:11 (4): 697-697
被引量:13
标识
DOI:10.3390/antiox11040697
摘要
Extensive research has been carried out to understand and elucidate the mechanisms of paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular diseases, neurological diseases, and inflammatory diseases. This review focuses on the relationship between PON1 and cancer. The data suggest that PON1, oxidative stress, chronic inflammation, and cancer are closely linked. Certainly, the gene expression of PON1 will remain challenging to study. Therefore, targeting PON1, redox-sensitive pathways, and transcription factors promise prevention and therapy in the development of several diseases, including cancer.
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