医学
伤口愈合
随机对照试验
临床终点
合子
外科
临床试验
双盲
生活质量(医疗保健)
内科学
传统医学
安慰剂
替代医学
护理部
病理
作者
Bruna Stéfany Bento de Sousa Teles,Bruna Stéfany Bento de Sousa Teles,Giovana Cardoso Xoteslem,Guilherme M. Gelfuso,Renata Costa Fortes,María Rita Carvalho Garbi Novaes
出处
期刊:Phlebology
[SAGE]
日期:2022-04-25
卷期号:37 (6): 460-468
被引量:1
标识
DOI:10.1177/02683555221088380
摘要
To evaluate the healing of venous ulcers in the lower limbs (VLU) using dressings with hydrocolloid gel associated with Syzygium cumini extract (SHG) compared to standard hydrocolloid gel dressings (HG).This prospective, double-blind, randomized trial recruited 90 patients with VLU divided into: dressings with SHG (n = 44) and dressings with HG (n = 46). Primary endpoint was healing in the 14th visit. Secondary endpoints were healing rate, complete healing during follow-up, and improvement in the pain scale and in quality of life.There were no significant between-group differences in healing (p = 0.15). The wound area made healing difficult (p = 0.008). Age, body mass index, and wound time demonstrated a tendency to worsen the healing. Positive culture for Pseudomonas aeruginosa resulted in 88% reduction in the healing risk (p < 0.0001).There was no difference between the dressings evaluated. The presence of Pseudomonas aeruginosa significantly impaired wound healing.
科研通智能强力驱动
Strongly Powered by AbleSci AI