默认模式网络
太空飞行
期限(时间)
神经科学
模式(计算机接口)
功能连接
心理学
认知心理学
计算机科学
物理
人机交互
工程类
航空航天工程
量子力学
作者
Yunxia Shen,Limin Peng,Hailong Chen,Pengfei Xu,Ke Lv,Zi Wei Xu,Hui Shen,Guohua Ji,Xiong Jiang-hui,Dewen Hu,Yinghui Li,Mingwu Lou,Ling‐Li Zeng,Lina Qu
出处
期刊:iScience
[Cell Press]
日期:2024-05-01
卷期号:27 (5): 109617-109617
标识
DOI:10.1016/j.isci.2024.109617
摘要
Long-term manned spaceflight and extraterrestrial planet settlement become the focus of space powers. However, the potential influence of closed and socially isolating spaceflight on the brain function remains unclear. A 180-day controlled ecological life support system integrated experiment was conducted, establishing a spaceflight analog environment to explore the effect of long-term socially isolating living. Three crewmembers were enrolled and underwent resting-state fMRI scanning before and after the experiment. We performed both seed-based and network-based analyses to investigate the functional connectivity (FC) changes of the default mode network (DMN), considering its key role in multiple higher-order cognitive functions. Compared with normal controls, the leader of crewmembers exhibited significantly reduced within-DMN and between-DMN FC after the experiment, while two others exhibited opposite trends. Moreover, individual differences of FC changes were further supported by evidence from behavioral analyses. The findings may shed new light on the development of psychological protection for space exploration.
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