Reductive Homologation of Nitroalkanes via Denitrative Aminoalkylation

We present the reductive homologation of nitroalkanes through the utilization of the denitrative aminoalkylation reaction. This transformation is accomplished by the radical–radical coupling of alkyl radicals derived from nitroalkanes and persistent aminoalkyl radicals. By capitalizing on the diverse α-functionalization of nitroalkanes, α,β-multifunctionalized amines can be readily accessed.