IL-22/IL-22RA1 Promotes Human Tenon’s Capsule Fibroblasts Proliferation and Regulates Fibrosis Through STAT3 Signaling Pathway

Although it is now understood that most antiglaucoma surgeries fail because of scarring of the filtering tract, the underlying mechanism remains to be elucidated. The present study investigated the mechanism by which the interleukin (IL)-22/IL-22 receptor alpha 1 (IL-22RA1) signaling pathway regulates scar formation in glaucoma patients.