期刊:American Chemical Society eBooks [American Chemical Society] 日期:2022-11-15
标识
DOI:10.1021/bk-2022-1420
摘要
High-Throughput Experimentation Drives Better Outcomes. High-throughput experimentation (HTE) is an emerging and powerful approach to problems in organic chemistry and homogeneous catalysis. This book is targeted at both experts and those new to the field who are seeking general perspectives and design principles for how to build and implement HTE capabilities. Specific examples of high-throughput experimental design and execution in the context of organic synthesis are included. Volume 2 contains targeted case studies from drug discovery, drug development, and reaction/catalyst discovery. These case studies are authored by practitioners in industry and academia, demonstrating through real-world context how a high-throughput mindset enables rapid optimization of existing chemistries and discovery of new reactivity.