免疫疗法
癌症
医学
化疗
彭布罗利珠单抗
透视图(图形)
肿瘤科
癌症免疫疗法
临床研究
第一行
重症监护医学
内科学
计算机科学
人工智能
作者
Jianzheng Wang,Shuiping Tu,Vivek P. Chavda,Zhe‐Sheng Chen,Xiaobing Chen
标识
DOI:10.1016/j.drudis.2022.103343
摘要
Many exploratory clinical studies have been conducted on immune checkpoint inhibitors (ICIs) as new therapeutic approaches for the first-line treatment of patients with advanced gastric cancer. Despite varying interpretations of the successes and failures of this clinical research, most analyses have focused on the results from the perspective of exploring the superiority of immunotherapy. Consequently, the role of chemotherapy as an important partner of immunotherapy in first-line combination therapy regimens for gastric cancer has attracted less attention. Here, we explore and analyze first-line immunotherapies for gastric cancer from the perspective of chemotherapy, to understand reasons for the failure of studies and to indicate directions for future clinical research.
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