肠道菌群
微生物群
生物
免疫系统
免疫学
疾病
粘液
炎症性肠病
丁酸盐
寄主(生物学)
微生物学
医学
生物信息学
食品科学
内科学
生态学
发酵
作者
Francesco Suriano,Eva Nyström,Domenico Sergi,Jenny Gustafsson
标识
DOI:10.3389/fimmu.2022.953196
摘要
The intestinal tract is an ecosystem in which the resident microbiota lives in symbiosis with its host. This symbiotic relationship is key to maintaining overall health, with dietary habits of the host representing one of the main external factors shaping the microbiome-host relationship. Diets high in fiber and low in fat and sugars, as opposed to Western and high-fat diets, have been shown to have a beneficial effect on intestinal health by promoting the growth of beneficial bacteria, improve mucus barrier function and immune tolerance, while inhibiting pro-inflammatory responses and their downstream effects. On the contrary, diets low in fiber and high in fat and sugars have been associated with alterations in microbiota composition/functionality and the subsequent development of chronic diseases such as food allergies, inflammatory bowel disease, and metabolic disease. In this review, we provided an updated overview of the current understanding of the connection between diet, microbiota, and health, with a special focus on the role of Western and high-fat diets in shaping intestinal homeostasis by modulating the gut microbiota.
科研通智能强力驱动
Strongly Powered by AbleSci AI