Review on LC-NMR Hyphenated Technique

A hyphenated technique refers to the integration of two distinct analytical methodologies to facilitate seamless interfacing. Typically, this involves the combination of chromatographic techniques with spectroscopic methods. LC-NMR, an influential analytical tool, has been instrumental in resolving intricate mixtures. LC-NMR, a hyphenated system that merges liquid chromatography (LC) with nuclear magnetic resonance (NMR), is a meticulously organized analytical approach extensively applied across various domains. These applications encompass the analysis of metabolites, profiling drug impurities, elucidating molecular structures, identifying volatile oils, scrutinizing pesticides, and investigating other natural products.