Highly Efficient Base Catalyzed N‐alkylation of Amines with Alcohols and β‐Alkylation of Secondary Alcohols with Primary Alcohols

The Cover Feature represents two different roads available to carry out the N-alkylation of amines with alcohols. The first road is wide and taken by many people; it consists of transition metal catalysis operating via the well-known “borrowing-hydrogen” pathway. In contrast, the findings reported by M. T. Johnson, O. F. Wendt and co-workers in their Research Article lays out a road less travelled, using the presence of air along with catalytic amount of base to reach the final goal. As indicated by the magnification, the methodology has a broader scope than shown and can be applied to similar reactions, one example in the report being the β-alkylation of secondary alcohols with primary alcohols. More information can be found in the Research Article by M. T. Johnson, O. F. Wendt and co-workers.