医学
横纹肌溶解症
原发性醛固酮增多症
低钾血症
介绍(产科)
儿科
肌痛
继发性高血压
急性肾损伤
重症监护医学
内科学
外科
血压
作者
Everardo Josué Díaz‐López,Rocío Villar-Taibo,Gemma Rodríguez-Carnero,Antía Fernández‐Pombo,Roberto Garcia-Peino,Manuel Narciso Blanco-Freire,Alberto Pena-Dubra,Teresa Prado‐Moraña,Irea- Fernández-Xove,Edurne Pérez-Béliz,José Cameselle‐Teijeiro,Á. Hermida Ameijeiras,Miguel Ángel Martínez Olmos
标识
DOI:10.3389/fendo.2023.1257078
摘要
Severe hypokalaemia causing rhabdomyolysis (RML) in primary aldosteronism (PA) is a rare entity, and only a few cases have been reported over the last four decades. This systematic review and case report aims to gather all published data regarding a hypokalaemic RML as presentation of PA in order to contribute to the early diagnosis of this extremely rare presentation. With the use of PubMed Central, EMBASE, and Google Scholar, a thorough internet-based search of the literature was conducted to identify articles and cases with RML secondary to hypokalaemia due to PA between June 1976 and July 2023. The case study concerns a 68-year-old male patient with hypokalaemic RML at presentation of PA. In the systematic review of the literature, 37 cases of RML secondary to hypokalaemia due to PA have been reported to date. In summary, the median age was 47.5 years, the male/female ratio was 17/21, all patients presented symptoms (weakness and/or myalgia), all the patients were hypertensive, and only four patients had complications with acute kidney injury (AKI). Although PA rarely presents with RML, it should be suspected when marked hypokalaemia and hypertension are also present. Early detection and management are essential to reduce the frequency of manifestations such as AKI.
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