Role of β-blockers in the cardiovascular disease continuum: a collaborative Delphi survey-based consensus from Asia-Pacific

医学 比索洛尔 德尔菲法 语句(逻辑) 家庭医学 冠状动脉疾病 心力衰竭 心脏病学 统计 政治学 数学 法学
作者
Saumitra Ray,Tiny Nair,J.P.S. Sawhney,Erwinanto,Azhari Rosman,Eugene B. Reyes,Leslie S. Go,Apichard Sukonthasarn,Aekarach Ariyachaipanich,Phạm Manh Hung,Harshal Chaudhari,Hardip Malhi
出处
期刊:Current Medical Research and Opinion [Informa]
卷期号:: 1-13
标识
DOI:10.1080/03007995.2023.2256218
摘要

Objective This Delphi method of consensus was designed to develop scientific statements for β-blockers in the continuum of cardiovascular diseases with a special focus on the role of bisoprolol.Methods Eleven experienced cardiologists from across the Asia-Pacific countries participated in two rounds of the survey. In the first round, experts were asked to rate agreement/disagreement with 35 statements across seven domains regarding the use of β-blockers for treating hypertension, heart failure, coronary artery diseases, co-morbidities as well as their safety profile, usage pattern, and pharmacokinetic variability. A consensus for a statement could be reached with >70% agreement.Results Except for seven statements, all attained consensus in the first round. In the second round that was conducted virtually, the experts re-appraised their ratings for the seven statements along with a critical appraisal of two additional statements that were suggested by experts in the preceding round. At the end of the second round, the final version included 36 statements (34 original statements, two statements suggested by experts, and the omission of one statement that did not attain consensus). The final version of statements in the second round was disseminated among experts for their approval followed by manuscript development.Conclusion Attainment of consensus for almost all statements reconfirms the clinical benefits of β-blockers, particularly β1-selective blockers for the entire spectrum of cardiovascular diseases.
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