鞣花单宁
鞣花酸
食品科学
发酵
植物乳杆菌
秀丽隐杆线虫
化学
活性氧
生物化学
生物
细菌
抗氧化剂
多酚
乳酸
基因
遗传学
作者
Mengwei Zhang,Shumao Cui,Bingyong Mao,Qiuxiang Zhang,Jianxin Zhao,Xin Tang,Wei Chen
标识
DOI:10.1021/acs.jafc.3c01062
摘要
Urolithin, intestinal microbiota metabolites of ellagitannin-rich foods, exhibit anti-aging activities. However, urolithin A is significantly superior to other types of urolithin with regard to this anti-aging function. This study aimed to screen edible urolithin A-producing strains of bacteria and explore the corresponding anti-aging efficacy of fermented products produced by these strains using Caenorhabditis elegans as a model. Our results showed that the Lactobacillus plantarum strains CCFM1286, CCFM1290, and CCFM1291 converted ellagitannin to produce urolithin A; the corresponding yields of urolithin A from these strains were 15.90 ± 1.46, 24.70 ± 0.82, and 32.01 ± 0.97 μM, respectively. Furthermore, it was found that the pomegranate juice extracts fermented by the CCFM1286, CCFM1290, and CCFM1291 strains of L. plantarum could extend lifespan by 26.04 ± 0.12, 32.05 ± 0.14, and 46.33 ± 0.12%, respectively, by improving mitochondrial function and/or reducing reactive oxygen species levels. These findings highlight the potential application of this fermentation in the subsequent development of anti-aging products.
科研通智能强力驱动
Strongly Powered by AbleSci AI