Synthesis of gem-Difluorinated Pentacyclic Indenopyrazolopyrazolones via Rh(III)-Catalyzed Cascade C-H Functionalization/[3+2] Dipolar Cycloaddition

By defining the gem-difluorocyclopropenyl acetates as versatile coupling partners, we have realized the Rh(III)-catalyzed cascade C-H functionalization/[3+2] dipolar cycloaddition of azomethine imines, which delivered a variety of gem-difluorinated pentacyclic indenzopyrazolpyrazolone...