Association of cardiovascular fibrosis, remodeling, and dysfunction with frailty, pre-frailty, and functional performance: the Multi-Ethnic Study of Atherosclerosis (MESA)

Cardiovascular disease is associated with higher incidence of frailty. However, the nature of the mechanisms underlying this association remains unclear. The purpose of this study is to identify cardiovascular phenotypes most associated with physical frailty and functional performance in the Multi-Ethnic Study of Atherosclerosis (MESA).