Contemporary Review of the Management and Treatment of Young Breast Cancer Patients

医学 乳腺癌 肿瘤科 内科学 妇科 癌症
作者
Brooke Vuong,Ana I Jacinto,Sharon B. Chang,Gillian Kuehner,Alison Savitz
出处
期刊:Clinical Breast Cancer [Elsevier]
标识
DOI:10.1016/j.clbc.2024.06.001
摘要

Approximately 11% of all new breast cancer cases annually are diagnosed in young women, and this continues to be the leading cause of death in women age 20 to 49. Young, premenopausal breast cancer patients present with more advanced stages and with a higher proportion of aggressive subtypes such as triple negative and HER2-enriched tumors. Recently, the United States Preventive Services Task Force (USPSTF) lowered the age threshold to initiate screening mammograms to age 40 to aid in earlier detection. Young age at diagnosis increases the likelihood for a pathogenic mutation, and genetic testing is recommended for all patients age 50 and younger. This population is often underrepresented in landmark clinical trials, and data is extrapolated for the treatment of young women with breast cancer. Despite there being no survival benefit to more extensive surgical treatments, such as mastectomy or contralateral prophylactic mastectomy, many patients opt against breast conservation. Young patients with breast cancer face issues related to treatment toxicities, potential overtreatment of their disease, mental health, sexual health, and fertility preservation. This unique population requires a multidisciplinary care team of physicians, surgeons, genetic counselors, fertility specialists, mental health professionals, physical therapists, and dieticians to provide individualized, comprehensive care. Our aim is to (1) provide a narrative review of retrospective studies, relevant society guidelines, and clinical trials focused on the contemporary treatment and management of YBC patients and (2) discuss important nuances in their care as a guide for members of their multidisciplinary treatment team.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
优美的听蓉完成签到,获得积分10
1秒前
1秒前
2秒前
柠檬完成签到,获得积分10
2秒前
lw发布了新的文献求助10
3秒前
西柚完成签到 ,获得积分10
3秒前
li发布了新的文献求助10
4秒前
4秒前
4秒前
4秒前
4秒前
贵金属LiLi完成签到 ,获得积分10
5秒前
蘑菇点点发布了新的文献求助10
5秒前
深情安青应助淡定的疾采纳,获得20
5秒前
有余完成签到,获得积分10
6秒前
满三江完成签到,获得积分10
6秒前
鸡毛发布了新的文献求助10
7秒前
7秒前
8秒前
一拳一个小欧阳完成签到 ,获得积分10
8秒前
Bubble发布了新的文献求助10
8秒前
王大壮发布了新的文献求助10
9秒前
ZHANG发布了新的文献求助30
9秒前
尘埃之影完成签到,获得积分10
9秒前
Lawliet发布了新的文献求助10
10秒前
Aliothae发布了新的文献求助10
11秒前
爱胡生发布了新的文献求助10
11秒前
NexusExplorer应助虚心曼容采纳,获得10
11秒前
12秒前
bkagyin应助vc采纳,获得10
12秒前
深情安青应助dalong采纳,获得10
13秒前
13秒前
15秒前
团结友爱完成签到,获得积分10
15秒前
罗博超完成签到,获得积分10
16秒前
愉快的真应助有余采纳,获得10
16秒前
17秒前
怡宝完成签到,获得积分10
18秒前
Liyu发布了新的文献求助10
18秒前
高分求助中
Sustainability in Tides Chemistry 2000
Microlepidoptera Palaearctica, Volumes 1 and 3 - 13 (12-Volume Set) [German] 1122
Дружба 友好报 (1957-1958) 1000
The Data Economy: Tools and Applications 1000
Mantiden - Faszinierende Lauerjäger – Buch gebraucht kaufen 700
PraxisRatgeber Mantiden., faszinierende Lauerjäger. – Buch gebraucht kaufe 700
A Dissection Guide & Atlas to the Rabbit 600
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3101379
求助须知:如何正确求助?哪些是违规求助? 2752746
关于积分的说明 7620795
捐赠科研通 2405017
什么是DOI,文献DOI怎么找? 1276094
科研通“疑难数据库(出版商)”最低求助积分说明 616692
版权声明 599058