Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis

医学对乙酰氨基酚病危器官功能障碍败血症重症监护医学危重病多器官功能障碍综合征内科学麻醉

作者

Lorraine B. Ware,D. Clark Files,Alpha A. Fowler,Michael S. Aboodi,Neil R. Aggarwal,Roy G. Brower,Steven Y. Chang,Ivor S. Douglas,Scott A. Fields,Andrea S. Foulkes,Adit A. Ginde,Estelle S. Harris,Gregory W. Hendey,R. Duncan Hite,Weixing Huang,Poying Lai,Kathleen D. Liu,Bruce Thompson,Michael A. Matthay,Jay S. Steingrub,Howard A. Smithline,Mark Tidswell,Lori Kozikowski,Sherell Thorton-Thompson,Lesley DeSouza,Cynthia Kardos,Sarah Romain,Scott Oullette,Peter C. Hou,Rebecca M. Baron,Christopher J. Hansen,Víctor Pinto Plata,Yuxiu Lei,Richard R. Riker,Christine Lord,Meghan Searight,Nathan I. Shapiro,Daniel Talmor,Valerie Banner‐Goodspeed,Bryan Stenson,Joshua Ellis,Alon Dagan,Tatyana Shilvkina,Rupinder Sekhon,Carlo Ottanelli,Ana Grafals,Kim Redman,M. Das,Nadim Kattouf,Alessio Barca,Alexander Weingart,Michael R. Filbin,Kathryn A. Hibbert,Blair A. Parry,Justin Margolin,Alan E. Jones,James Galbraith,Utsav Nandi,Carolyn M. Hendrickson,Kirsten N. Kangelaris,Taarini Hariharan,Rachel Groper,Kimia Ashktorab,Anika Agrawal,Emma Schmiege,Hanjing Zhuo,Carolyn Leroux,Steven Y. Chang,Gregory W. Hendey,George Lim,Hena Sihota,Joseph E. Levitt,Jenny G. Wilson,Angela J. Rogers,Rosemary Vojnik,Shreya Battu,Cynthia Pérez,Timothy E. Albertson,Brian Morrissey,Katherine Wick,Erin Hardy,Ruchira Puri,Tessa Hafenstein,Alyssa Hughes,Eyad Almasri,Shelly Hibbard,Bela Patel,Bindu Akkanti,Pratik Doshi,Gabriel Patarroyo‐Aponte,Ryan Huebinger,Elizabeth Vidales,Idorenyin Udoh-Bradford,Neil R. Aggarwal,Adit A. Ginde,Jeffrey McKeehan,Carrie Higgins,Ashley Licursi,Jennifer Fickes-Siler,Suzanne Slaughter,Emily L. Johnson,Ivor S. Douglas,Jason S. Haukoos,Stacy A. Trent,T. Hiller,Carolynn Lyle,Ana Garcia,Stephnie Gravitz,D. Tran,Mia Lundin,Julie Dunn,Eric Stevens,Nikiah Nudell,Bridget A. Baxter,Scott Bins,Brittany Smoot,Nichol Huckins,Ivan Co,Pauline K. Park,Robert C. Hyzy,Kristine Nelson,J. Victor Jiminez,Normal Olbrich,Jakob I. McSparron,Elizabeth Munroe,Philip Choi,Shijing Jia,Robert Sherwin,Thomas Mazzocco,Lauren Buck,Teja S. Pandrangi,Jennifer Swiderek,Emanuel P. Rivers,Jasreen Gill,Jacqueline Day,Anja Kathrin Jaehne,Michelle N. Gong,Ari Moskowitz,Amira Mohamed,Martha Torres,Ofelia Garcı́a,Luke Andrea,Brenda Lopez,Sabah Boujid,Manuel Hache Marliere,Lynne D. Richardson,Samuel Acquah,Neha Goel,Patrick Maher,Cameron Hypes,Elizabeth Salvagio Campbell,Anitza Lopez,Mary Labus,Kristin Hudock,R. Duncan Hite,Hammad Tanzeem,Harshada More,Ashraf Khallaf,Benjamin Williams,Abhijit Duggal,Siddharth Dugar,Simon Mucha,Omar Mehkri,Kiran Ashok,Caleb Chang,Sonal Pannu,Matthew C. Exline,Henry E. Wang,Sarah Karow,Gabrielle Swoope,Maryiam Khan,David A. Smith,Madison So,Elli Schwartz,M. Kelly Johnson,D. Clark Files,Chawick Miller,Kevin W. Gibbs,Lori Flores,Lisa Parks,Leigha Landreth,Lauren E. Koehler,Alpha A. Fowler,Marjolein de Wit,Jessica Mason,Aamer Syed,Xian Qiao,Kate Mitchell,Nicholas J. Johnson,Bryce R. H. Robinson,Stephanie J. Gundel,Megan Fuentes,Maranda Newton,Emily Peterson,Kathryn Thompson,Armando Rodríguez,Thomas C Paulsen,Ashdeep Kaur,Catherine L. Hough,Molly Ward,Madeline McDougal,Efrain Chavez Martinez,Edlyn Wolwowicz,Otmar Borchard,Akram Khan,Peter Chen,Ethan Paschal,Po-En Chen,Yunkee Choi-Kuaea,Shane O'Mahony,Julie A. Wallick,Alexandria M. Duven,Dakota D. Fletcher,Alexandria Weissman,Donald M. Yealy,Denise Scholl,Bryan J. McVerry,David T. Huang,Michael A. Turturro,Derek C. Angus,Jordan B. Schooler,Lawrence E. Kass,Nina T. Gentile,Nathaniel Marchetti,Hannah Reimer,Andrew J. Goodwin,Abby Grady,Caitlan T. Lematty,Charles R. Terry,Melissa Blender,Jeffrey M. Sturek,Mark Sochor,Mary Faith Marshall,Ashley Simpson,Nikhil Patel,Bryce Taylor,Daxita Patem,Jessica Kearney-Bryan,Daniel B. Knox,Lindsay Leither,Michael J. Lanspa,Samuel M. Brown,Ithan D. Peltan,Andrew Gray,Valerie Aston,Tyler Burke,Joshua Jeppsen,Hunter Marshall,Carolyn Klippel,Brent Armbruster,Darrin Applegate,Estelle S. Harris,Elizabeth A. Middleton,Sean J. Callahan,Lindsey Waddoups,Misty B. Yamane,Macy A G Barrios,Nancy Wickersham,Nathan D. Putz,Samantha Gonski,Jason Lin,Nury Lee,Todd W. Rice,Lorraine B. Ware,Wesley H. Self,Margaret Hays,Matthew W. Semler,Liza Frawley,David Schoenfeld,Bruce Thompson,Ivor S. Douglas,Nancy Ringwood,Cathryn F. Oldmixon,Richard P. Morse,Ariela Muzikansky,Laura Fitzgerald,Adrian Lagakos,Weixing Huang,Pouing Lai,Grace Carey,Roy G. Brower,Antonello Punturieri,Lora A. Reineck,Karen Beinstock,Ejigayehu Demissie,Michelle Freemer,James P. Kiley,Lauren Kunz,Mario Stylianou,Myron Maclawiw,Gail Weinmann,Laurie J. Morrison,Daniel Brodie,Charles B. Cairns,Mark N. Gillespie,Richard J. Kryscio,Daman Scales,Robert D. Truog,Polly E. Parsons,Jason D. Christie,Neal W. Dickert,Deborah B. Diercks,Jesse Hall,Nicholas J. Horton,Mitchell Levy,Mark Seigel,Ian Steill,Laurie Zoloth,David B. Page,Derek W. Russell,Donna S. Harris,Sheetal Gandotra

出处

期刊：JAMA [American Medical Association]
日期：2024-05-19 卷期号：332 (5): 390-390 被引量：2

链接

nih.govdoi.org

标识

DOI：10.1001/jama.2024.8772

摘要

Acetaminophen (paracetamol) has many pharmacological effects that might be beneficial in sepsis, including inhibition of cell-free hemoglobin-induced oxidation of lipids and other substrates.

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Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis

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