Toward inclusive global governance of human genome editing

Pesticidal proteins from bacteria, such as Bacillus thuringiensis and Lysinibacillus sphaericus, are widely used as biocontrol agents against various mosquito vectors of human disease. Tpp49Aa1/Cry48Aa1 from L. sphaericus are required as a ...The Lysinibacillus sphaericus proteins Tpp49Aa1 and Cry48Aa1 can together act as a toxin toward the mosquito Culex quinquefasciatus and have potential use in biocontrol. Given that proteins with sequence homology to the individual proteins can have ...