纳米技术
贵金属
致病菌
纳米颗粒
纳米化学
人类健康
材料科学
细菌
计算机科学
生化工程
金属
医学
工程类
生物
环境卫生
冶金
遗传学
作者
Shouzhi Yang,Qi-Ao Liu,Yanling Liu,Guo-jun Weng,Jian Zhu,Jian-Jun Li
标识
DOI:10.1007/s00604-021-04885-z
摘要
Pathogenic bacteria have become a huge threat to social health and economy for their frighteningly infectious and lethal capacity. It is quite important to make a diagnosis in advance to prevent infection or allow a rapid treatment after infection. Noble metal nanoparticles, due to their unique physicochemical properties, especially optical properties, have drawn a great attention during the past decades and have been widely applied into all kinds of fields related to human health. By utilizing these noble metal nanoparticles, optical diagnosis platforms towards pathogenic bacteria have emerged continually, providing highly sensitive, selective, and particularly facile detection tools for clinic or point-of-care diagnosis. This review summarizes the recent development in this field. It begins with a brief introduction of pathogenic bacteria and noble metal nanoparticles. And then, optical detection methods are systematically discussed in three distinct aspects. In addition to these proof-of-concept methods, corresponding algorithms and point-of-care detection devices are also described. Finally, the review ends up with subjective views on present limitations and some appropriate advice for future research directions.
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