In T2DM, weekly insulin icodec did not differ from daily glargine for reducing HbA1c or significant/severe hypoglycemia

ACP Journal ClubMarch 2021In T2DM, weekly insulin icodec did not differ from daily glargine for reducing HbA1c or significant/severe hypoglycemiaTomás P. Griffin, MB, BCh, BAO, MSc, Dip Clin Ed, Sean F. Dinneen, MD, MScTomás P. Griffin, MB, BCh, BAO, MSc, Dip Clin EdGalway University Hospitals, Galway, Ireland (T.P.G., S.F.D.)Search for more papers by this author, Sean F. Dinneen, MD, MScGalway University Hospitals, Galway, Ireland (T.P.G., S.F.D.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJ202103160-034 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationRosenstock J, Bajaj HS, Janež A, et al. Once-weekly insulin for type 2 diabetes without previous insulin treatment. N Engl J Med. 2020:383:2107-16. https://pubmed.ncbi.nlm.nih.gov/32960514Clinical Impact RatingsGIM/FP/GP: Endocrinology: References1 Qiao Q, Ouwens MJ, Grandy S, et al. Adherence to GLP-1 receptor agonist therapy administered by once-daily or once-weekly injection in patients with type 2 diabetes in Germany. Diabetes Metab Syndr Obes. 2016;9:201-5. [PMID: 27418849] Google Scholar2 American Diabetes Association. 6. Glycemic targets: standards of medical care in diabetes–2020. Diabetes Care. 2020;43:S66–76. [PMID: 31862749] Google Scholar3 Zinman B, Philis-Tsimikas A, Cariou B, et al. Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care. 2012;35:2464-71. [PMID: 23043166] Google Scholar Author, Article, and Disclosure InformationAffiliations: Galway University Hospitals, Galway, Ireland (T.P.G., S.F.D.)Disclosures: The commentators have disclosed no conflicts of interest. The forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-7314.This article was published at Annals.org on 2 March 2021. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byWeekly Insulin Becoming a Reality March 2021Volume 174, Issue 3Page: JC34KeywordsAlgorithmsCognitive impairmentGlucoseHbA1cHemoglobinHypoglycemiaHypoglycemicsInsulinSafetyType 2 diabetes ePublished: 2 March 2021 Issue Published: March 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...