英夫利昔单抗
医学
克罗恩病
炎症性肠病
回肠炎
微阵列
基因表达
溃疡性结肠炎
活检
内科学
基因
胃肠病学
结肠炎
微阵列分析技术
疾病
生物
生物化学
作者
Ingrid Arijs,Roel Quintens,Leentje Van Lommel,Kristel Van Steen,Gert De Hertogh,Katleen Lemaire,Anica Schraenen,Clémentine Perrier,Gert Van Assche,Séverine Vermeire,Karel Geboes,Frans Schuit,Paul Rutgeerts
出处
期刊:Inflammatory Bowel Diseases
[Oxford University Press]
日期:2010-04-07
卷期号:16 (12): 2090-2098
被引量:157
摘要
BackgroundInfliximab (IFX) has become the mainstay of therapy of refractory Crohn's disease (CD). However, a subset of patients shows incomplete or no response to this agent. In this study we investigated whether we could identify a mucosal gene panel to predict (non)response to IFX in CD.
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